{"id":709513,"date":"2021-11-29T11:50:42","date_gmt":"2021-11-29T15:50:42","guid":{"rendered":"http:\/\/spaceweekly.com\/?p=709513"},"modified":"2021-11-29T11:50:42","modified_gmt":"2021-11-29T15:50:42","slug":"mechanism-for-insensitivity-to-important-antimalarial-drug-in-new-pathogen-variant-discovered","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=709513","title":{"rendered":"Mechanism for insensitivity to important antimalarial drug in new pathogen variant discovered"},"content":{"rendered":"<p>Malaria is one of the most dangerous infectious diseases. The causative pathogens are microorganisms of the genus Plasmodium. A particularly dangerous form of the disease is caused by Plasmodium falciparum. Artemisinin is one of the most important antimalarial drugs against this parasite. However, in a mutant of the pathogen that is now spreading, the effect of artemisinin is limited. A team of researchers around Robin Schumann, a biochemist from Kaiserslautern, has now found the mechanism behind this: A protein that is involved in the development of the parasite is misfolded. The study has been published in the journal Redox Biology.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/phys.org\/news\/2021-11-mechanism-insensitivity-important-antimalarial-drug.html\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Mechanism for insensitivity to important antimalarial drug in new pathogen variant discovered<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: Phys.org&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Malaria is one of the most dangerous infectious diseases. The causative pathogens are microorganisms of the genus Plasmodium. A particularly dangerous form of the disease is caused by Plasmodium falciparum.&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41],"tags":[],"class_list":["post-709513","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-phys-org"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/709513","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=709513"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/709513\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=709513"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=709513"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=709513"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}