{"id":719538,"date":"2022-03-17T09:47:58","date_gmt":"2022-03-17T13:47:58","guid":{"rendered":"https:\/\/spaceweekly.com\/?p=719538"},"modified":"2022-03-17T09:47:58","modified_gmt":"2022-03-17T13:47:58","slug":"alzheimers-protective-immune-cells-active-decades-before-symptom-onset","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=719538","title":{"rendered":"Alzheimer\u2019s: Protective immune cells active decades before symptom onset"},"content":{"rendered":"<p>In individuals with a genetic predisposition to Alzheimer&#8217;s disease, the immune cells of the brain &#8212; the &#8216;microglia&#8217; &#8212; start exerting a protective effect up to two decades before the first symptoms appear. A team draws this conclusion based on a study of more than 200 volunteers. In light of their study data, the scientists consider modulating the activity of microglia to be a promising therapeutic approach. To this end, they aim to develop drugs that target a cellular receptor called TREM2.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/www.sciencedaily.com\/releases\/2022\/03\/220317094758.htm\" target=\"_blank\" rel=\"nofollow noopener\">Alzheimer\u2019s: Protective immune cells active decades before symptom onset<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: ScienceDaily&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In individuals with a genetic predisposition to Alzheimer&#8217;s disease, the immune cells of the brain &#8212; the &#8216;microglia&#8217; &#8212; start exerting a protective effect up to two decades before the&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-719538","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genaero"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/719538","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=719538"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/719538\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=719538"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=719538"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=719538"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}