{"id":721306,"date":"2022-04-14T11:07:50","date_gmt":"2022-04-14T15:07:50","guid":{"rendered":"http:\/\/spaceweekly.com\/?p=721306"},"modified":"2022-04-14T11:07:50","modified_gmt":"2022-04-14T15:07:50","slug":"colon-cancer-how-mutation-of-the-apc-gene-disrupts-lymphocyte-migration","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=721306","title":{"rendered":"Colon cancer: How mutation of the APC gene disrupts lymphocyte migration"},"content":{"rendered":"<p>In patients with familial adenomatous polyposis, a genetic disease predisposing to colon cancer, mutations of the APC gene induce the formation of intestinal polyps, but also reduce immune system activity. In a new study, researchers describe the mechanisms that modify the structure of T lymphocytes and hinder their migration towards the tumors to be destroyed. This discovery provides new perspectives on the migration of immune cells, a key process in antitumor immune defense.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/www.sciencedaily.com\/releases\/2022\/04\/220414110750.htm\" target=\"_blank\" rel=\"nofollow noopener\">Colon cancer: How mutation of the APC gene disrupts lymphocyte migration<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: ScienceDaily&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In patients with familial adenomatous polyposis, a genetic disease predisposing to colon cancer, mutations of the APC gene induce the formation of intestinal polyps, but also reduce immune system activity.&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-721306","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genaero"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/721306","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=721306"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/721306\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=721306"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=721306"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=721306"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}