{"id":728263,"date":"2022-06-28T17:01:39","date_gmt":"2022-06-28T21:01:39","guid":{"rendered":"http:\/\/spaceweekly.com\/?p=728263"},"modified":"2022-06-28T17:01:39","modified_gmt":"2022-06-28T21:01:39","slug":"double-duty-early-research-reveals-how-a-single-drug-delivers-twice-the-impact-in-fragile-x","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=728263","title":{"rendered":"Double duty: Early research reveals how a single drug delivers twice the impact in fragile X"},"content":{"rendered":"<p>A new study shows how two major pathways &#8212; AKT and NMD (nonsense-mediated mRNA decay) &#8212; interact in the context of fragile X syndrome. Researchers also found that Afuresertib, a drug currently being tested in phase 1 and 2 clinical trials for several types of cancer, inhibits both pathways in neural stem cells that mimic the disease, leading the cells to act more like typical, non-disease cells.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/www.sciencedaily.com\/releases\/2022\/06\/220628170139.htm\" target=\"_blank\" rel=\"nofollow noopener\">Double duty: Early research reveals how a single drug delivers twice the impact in fragile X<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: ScienceDaily&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new study shows how two major pathways &#8212; AKT and NMD (nonsense-mediated mRNA decay) &#8212; interact in the context of fragile X syndrome. Researchers also found that Afuresertib, a&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-728263","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genaero"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/728263","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=728263"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/728263\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=728263"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=728263"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=728263"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}