{"id":732714,"date":"2022-08-18T14:57:42","date_gmt":"2022-08-18T18:57:42","guid":{"rendered":"http:\/\/spaceweekly.com\/?p=732714"},"modified":"2022-08-18T14:57:42","modified_gmt":"2022-08-18T18:57:42","slug":"study-reveals-ligand-recognition-mechanism-of-orphan-receptor-gpr119","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=732714","title":{"rendered":"Study reveals ligand recognition mechanism of orphan receptor GPR119"},"content":{"rendered":"<p>Metabolic diseases, including diabetes, fatty liver, and obesity, have become a major &#8220;killer&#8221; affecting human health. Studies have shown that some orphan receptors could be targets for the treatment of these diseases. GPR119, also known as glucose-dependent insulinotropic receptor, is an orphan receptor in the G protein-coupled receptor (GPCR) superfamily. Activation of GPR119 can stimulate the secretion of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulin-releasing polypeptide (GIP), two hormones that are important for regulating the balance of glucose metabolism in the body.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/phys.org\/news\/2022-08-reveals-ligand-recognition-mechanism-orphan.html\" target=\"_blank\" rel=\"nofollow noopener\">Study reveals ligand recognition mechanism of orphan receptor GPR119<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: Phys.org&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Metabolic diseases, including diabetes, fatty liver, and obesity, have become a major &#8220;killer&#8221; affecting human health. Studies have shown that some orphan receptors could be targets for the treatment of&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41],"tags":[],"class_list":["post-732714","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-phys-org"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/732714","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=732714"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/732714\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=732714"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=732714"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=732714"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}