{"id":747338,"date":"2023-02-03T13:56:02","date_gmt":"2023-02-03T17:56:02","guid":{"rendered":"http:\/\/spaceweekly.com\/?p=747338"},"modified":"2023-02-03T13:56:02","modified_gmt":"2023-02-03T17:56:02","slug":"development-of-a-versatile-method-to-synthesize-functional-mrnas-with-diverse-5-cap-structures","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=747338","title":{"rendered":"Development of a versatile method to synthesize functional mRNAs with diverse 5&#039; cap structures"},"content":{"rendered":"<p>Synthetic mRNAs are explored rigorously for their potential as an effective genetic vector for basic research and clinical applications. Natural mRNAs have a structure on their leading (5&#8242;) ends\u2014called the 5&#8242; cap\u2014that regulates their stability and translational activity. As such, there is a tremendous effort to devise new methods to chemically modify and generate functional 5&#8242; cap structures.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/phys.org\/news\/2023-02-versatile-method-functional-mrnas-diverse.html\" target=\"_blank\" rel=\"nofollow noopener\">Development of a versatile method to synthesize functional mRNAs with diverse 5&#8242; cap structures<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: Phys.org&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Synthetic mRNAs are explored rigorously for their potential as an effective genetic vector for basic research and clinical applications. Natural mRNAs have a structure on their leading (5&#8242;) ends\u2014called the&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41],"tags":[],"class_list":["post-747338","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-phys-org"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/747338","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=747338"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/747338\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=747338"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=747338"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=747338"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}