{"id":747803,"date":"2023-02-09T12:47:32","date_gmt":"2023-02-09T16:47:32","guid":{"rendered":"https:\/\/spaceweekly.com\/?p=747803"},"modified":"2023-02-09T12:47:32","modified_gmt":"2023-02-09T16:47:32","slug":"tiny-but-mighty-gene-fragments-are-crucial-for-maintaining-blood-glucose-levels","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=747803","title":{"rendered":"&#039;Tiny but mighty&#039; gene fragments are crucial for maintaining blood glucose levels"},"content":{"rendered":"<p>Microexons, tiny fragments of genes that are just 3-27 nucleotides long, are known to play a &#8216;tiny but mighty&#8217; role in neuronal cells. Through RNA splicing, microexons sculpt the surfaces of proteins in a highly precise manner, performing microsurgery on the nervous system&#8217;s proteins. According to a new study, microexons are also crucial for pancreatic function and regulating blood glucose levels. The microexons are located on more than a hundred genes, including some critical for insulin secretion and type-2 diabetes risk. The researchers believe the discovery could lead to new high-precision treatments for type-2 diabetes, for example by repurposing existing treatments that already exploit RNA splicing mechanisms to treat other types of diseases.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/www.sciencedaily.com\/releases\/2023\/02\/230209114732.htm\" target=\"_blank\" rel=\"nofollow noopener\">&#8216;Tiny but mighty&#8217; gene fragments are crucial for maintaining blood glucose levels<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: ScienceDaily&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Microexons, tiny fragments of genes that are just 3-27 nucleotides long, are known to play a &#8216;tiny but mighty&#8217; role in neuronal cells. Through RNA splicing, microexons sculpt the surfaces&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-747803","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genaero"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/747803","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=747803"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/747803\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=747803"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=747803"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=747803"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}