{"id":749377,"date":"2023-03-01T11:15:03","date_gmt":"2023-03-01T15:15:03","guid":{"rendered":"http:\/\/spaceweekly.com\/?p=749377"},"modified":"2023-03-01T11:15:03","modified_gmt":"2023-03-01T15:15:03","slug":"degrading-modified-proteins-could-treat-alzheimers-other-undruggable-diseases","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=749377","title":{"rendered":"Degrading modified proteins could treat Alzheimer&#039;s, other &#039;undruggable&#039; diseases"},"content":{"rendered":"<p>Certain diseases, including Alzheimer&#8217;s, are currently considered &#8216;undruggable&#8217; because traditional small molecule drugs can&#8217;t interfere with the proteins responsible for the illnesses. But a new technique that specifically targets and breaks apart certain proteins &#8212; rather than just interfering with them &#8212; may offer a pathway toward treatment. Researchers have now designed a compound that targets and breaks down a post-translationally modified protein closely associated with Alzheimer&#8217;s disease.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/www.sciencedaily.com\/releases\/2023\/03\/230301101503.htm\" target=\"_blank\" rel=\"nofollow noopener\">Degrading modified proteins could treat Alzheimer&#8217;s, other &#8216;undruggable&#8217; diseases<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: ScienceDaily&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Certain diseases, including Alzheimer&#8217;s, are currently considered &#8216;undruggable&#8217; because traditional small molecule drugs can&#8217;t interfere with the proteins responsible for the illnesses. But a new technique that specifically targets and&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-749377","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genaero"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/749377","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=749377"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/749377\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=749377"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=749377"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=749377"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}