{"id":754515,"date":"2023-04-28T10:45:21","date_gmt":"2023-04-28T14:45:21","guid":{"rendered":"https:\/\/spaceweekly.com\/?p=754515"},"modified":"2023-04-28T10:45:21","modified_gmt":"2023-04-28T14:45:21","slug":"how-a-single-enzyme-unleashes-a-complex-dna-repair-process","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=754515","title":{"rendered":"How a single enzyme unleashes a complex DNA repair process"},"content":{"rendered":"<p>Our DNA is constantly exposed to damaging factors that can lead to aging and age-related diseases such as cancer. PARP1 is an important enzyme that facilitates the response to DNA damage by attaching chemical groups called ADP-ribose to proteins. Published in Molecular Cell, a new study by the Matic group at the Max Planck Institute for the Biology of Ageing has discovered a second, slower wave of PARP1 activity that regulates DNA repair in a more gradual way.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/phys.org\/news\/2023-04-enzyme-unleashes-complex-dna.html\" target=\"_blank\" rel=\"nofollow noopener\">How a single enzyme unleashes a complex DNA repair process<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: Phys.org&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Our DNA is constantly exposed to damaging factors that can lead to aging and age-related diseases such as cancer. PARP1 is an important enzyme that facilitates the response to DNA&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41],"tags":[],"class_list":["post-754515","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-phys-org"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/754515","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=754515"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/754515\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=754515"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=754515"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=754515"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}