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Researchers tested a treatment on cartilage and bone tissue cultures subjected to compressive impact injury and\u00a0<\/strong>found<\/strong>\u00a0differences in the metabolites and proteins released by cells in space and on Earth along with partial improvement in both gravity conditions. The findings suggest the treatment is safe and could help ensure the health of crew members on future missions and patients on Earth.<\/strong><\/p>\n Astronauts have high rates of musculoskeletal injuries, and post-traumatic osteoarthritis from joint injuries is a major contributor to disability across all ages on the ground.\u00a0MVP Cell-06\u00a0used cultures of human knee cartilage and bone cells from two donors to study how spaceflight affects musculoskeletal disease. Results could lead to ways to prevent and treat bone and cartilage degradation in astronauts and people on Earth following joint injury.<\/p>\n NASA and Roscosmos researchers examined brazing of an aluminum-silicon material and\u00a0<\/strong>found<\/strong>\u00a0that gravity had a moderate effect with small quantities of the alloy and a more significant effect with larger quantities. The finding could\u00a0<\/em>inform techniques for manufacturing on future space missions.<\/strong><\/p>\n SUBSA-BRAINS\u00a0examined capillary flow, interface reactions, and bubble formation during solidification of brazing alloys in microgravity. Brazing, which bonds similar and dissimilar materials at temperatures above 450\u00b0C, is a potential tool for construction, manufacture, and repair of space vehicles and habitats.<\/p>\n Analysis of the pain experience of two Axiom-1 astronauts\u00a0<\/strong>suggests<\/strong>\u00a0that spaceflight may affect sensory perception and regulation, a finding similar to previous studies. Researchers recommend developing measurement tools with greater sensitivity and questions that capture previous spaceflight experience and astronaut status (commercial or professional) to assess pain experiences.<\/strong><\/p>\n Astronauts frequently report pain during missions and after returning to Earth, particularly in the back and neck.\u00a0Microgravity Pain Sensation (Ax-1)\u00a0assessed how short-term exposure to microgravity affects pain sensation, biomechanics, bone physiology, and the musculoskeletal system.\u00a0Results\u00a0suggested that spaceflight may affect various aspects of sensory perception and regulation, and further investigation is needed to support development of countermeasures and treatments.<\/p>\n The 13th annual International Space Station Research and Development Conference (<\/strong>ISSRDC<\/strong>), sponsored by the ISS National Lab, brought together more than 900\u00a0leaders in academia, industry, and government to discuss the space station\u2019s role in future research and development.<\/strong><\/p>\n The event was held in Boston July 30 to Aug 1. Speakers included White House Office of Science and Technology Policy Assistant Director for Space Policy Jinni Meehan, NASA Associate Administrator Jim Free, NASA astronaut Stephen Bowen, and representatives from the\u00a0International Space Station\u00a0international and commercial partners.<\/p>\n<\/div>\n