{"id":794181,"date":"2025-03-08T14:56:04","date_gmt":"2025-03-08T19:56:04","guid":{"rendered":"https:\/\/spaceweekly.com\/?p=794181"},"modified":"2025-03-08T14:56:04","modified_gmt":"2025-03-08T19:56:04","slug":"how-humans-can-reinvent-themselves-to-live-on-other-worlds","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=794181","title":{"rendered":"How Humans Can Reinvent Themselves to Live on Other Worlds"},"content":{"rendered":"<p> <br \/>\n<\/p>\n<div id=\"\">\n<p>        <span><\/p>\n<p>            By Alan Boyle<\/p>\n<p>        <\/span><\/p>\n<p>      <span class=\"article-date\">March 8, 2025<\/span>\n    <\/p>\n<\/p><\/div>\n<div>\n<div class=\"text\">\n<p>Let\u2019s face it: Space is a hostile environment for humans. Even on Mars, settlers might have a hard time coping with potentially lethal levels of radiation, scarce resources and reduced gravity.<\/p>\n<p>In \u201cMickey 17\u201d \u2014 a new sci-fi movie from Bong Joon Ho, the South Korean filmmaker who made his mark with \u201cParasite\u201d \u2014 an expendable space traveler named Mickey (Robert Pattinson) is exposed over and over again to deadly risks. And every time he\u2019s killed, the lab\u2019s 3D printer just churns out another copy of Mickey.<\/p>\n<p>\u201cHe\u2019s dying to save mankind,\u201d the movie\u2019s poster proclaims.<\/p>\n<p>While it\u2019s possibly to create 3D-printed body parts for implantation, the idea of printing out a complete human body and restoring its backed-up memories is pure science fiction. Nevertheless, Christopher Mason, a Cornell University biomedical researcher who studies space-related health issues, is intrigued by the movie\u2019s premise.<\/p>\n<p>\u201cIf you could 3D print a body and perfectly reconstruct it, you could, in theory, learn a lot about a body that\u2019s put in a more dangerous situation,\u201d he says in the latest episode of the Fiction Science podcast. \u201cI think the concept of the movie is actually quite interesting.\u201d<\/p>\n<p>Mason explores the ways in which the human body can be optimized for living in space in a book titled \u201cThe Next 500 Years: Engineering Life to Reach New Worlds.\u201d He argues that it\u2019s up to us humans to ensure the long-term future of life in the universe by taking the tools of evolution into our own hands.<\/p>\n<p>Even if we\u2019re able to avoid blowing ourselves up, or succumbing to the effects of climate change, we have only about a billion years before the sun reaches a level of activity that would make Earth unlivable.<\/p>\n<p>\u201cI want to think about preserving life, which necessitates us going to other planets and eventually other stars,\u201d Mason says. \u201cBecause humans are the only species with an awareness of extinction, this gives us a unique duty toward life \u2026 what I call a deontogenic sort of principle, the genetic duty toward all life.\u201d<\/p>\n<p><em>Christopher Mason studies beneficial genetic changes. (Credit: Weill Cornell Medicine) <\/em><\/p>\n<p>The good news is that we can adjust to many of the rigors of spaceflight, at least temporarily. Mason and other researchers saw that when they monitored the health of NASA astronaut Scott Kelly during his nearly yearlong stint on the International Space Station in 2015-2016. They compared Kelly\u2019s physical and genetic profile with that of his twin brother, Mark Kelly, who was monitored down on Earth.<\/p>\n<p>The NASA-sponsored Twins Study found that Scott Kelly experienced changes in the ways that his genes and his immune system worked while he was in space \u2014 possibly because of radiation exposure and other space-related stresses.<\/p>\n<p>\u201cMore than 90% of these changes really seemed to come back to normal within a few months being back on Earth,\u201d Mason said. But some of the changes were longer-lasting.<\/p>\n<p>\u201cThere\u2019s this nagging question of this small percentage of genes and functions that were perturbed that we\u2019re still studying to this day in other crews, with SpaceX and other commercial providers,\u201d he said.<\/p>\n<p>The stresses of the space environment are likely to become more concerning as explorers and settlers go beyond Earth orbit and our planet\u2019s protective magnetic shield. Which gets us back to the things that can kill Mickey 17 and other earthly life forms.<\/p>\n<\/p><\/div>\n<div class=\"youtube-video\">\n<p>\n              <iframe src=\"https:\/\/www.youtube-nocookie.com\/embed\/osYpGSz_0i4\" frameborder=\"0\" allowfullscreen=\"\" style=\"position: absolute; top: 0; left: 0; width: 100%; height: 100%;\"><\/iframe>\n            <\/p>\n<\/p><\/div>\n<div class=\"text\">\n<p>Radiation is the top concern. The studies done to date suggest that astronauts could be exposed to cancer-causing levels of radiation during a three-year mission to Mars and back. Thick shielding could reduce the risk, but Mason suggests using genetics as well.<\/p>\n<p>\u201cFor example, tardigrades are these water bears that can survive even the vacuum of space and heavy doses of radiation,\u201d he says. \u201cWe\u2019ve made cells in my laboratory that can actually take a tardigrade gene and use it in a human cell, and have this increase of radiation resistance \u2014 an 80% decrease in the [DNA] damage that we observe.\u201d<\/p>\n<p>If scientists could use CRISPR-style gene-editing tools to insert the tardigrade gene into Mickey\u2019s genome, that might head off one of his deaths. In his book, Mason lists other genetic techniques that could improve the vision of space travelers, boost their immune response, or make it easier for them to \u201chibernate\u201d during a long trip.<\/p>\n<\/p><\/div>\n<div class=\"youtube-video\">\n<p>\n              <iframe src=\"https:\/\/www.youtube-nocookie.com\/embed\/TV7qAsp6x3w\" frameborder=\"0\" allowfullscreen=\"\" style=\"position: absolute; top: 0; left: 0; width: 100%; height: 100%;\"><\/iframe>\n            <\/p>\n<\/p><\/div>\n<div class=\"text\">\n<p>\u201cThe simplest one, I think, includes the ability to make all of your own amino acids and vitamins,\u201d Mason says. \u201cThe gene to make vitamin C, for example, is still embedded in all of our DNA. It\u2019s just been degraded, and it\u2019s no longer functional. But with a few small modifications, you can make your own vitamin C.\u201d<\/p>\n<p>As scientists learn more about health-related genes in humans and other species, and improve their gene-editing techniques, Mason thinks the challenges of spaceflight will become less daunting \u2014 not only for professional astronauts, but for the rest of us as well.<\/p>\n<p>\u201cYou could imagine a case where you can ethically and responsibly and safely modify someone to get them into space,\u201d Mason says. \u201cThat\u2019s not that far away.\u201d<\/p>\n<p>And if space travelers run into unexpected challenges on another world \u2014 for example, alien microbes on Mars \u2014 they wouldn\u2019t have to handle it on their own.<\/p>\n<p>\u201cI talk a bit in the book about a \u2018point-to-point biology\u2019 concept, where weird things might appear on Mars, but there\u2019s not a lot of resources there to do high-throughput screening, or high-dimensional characterization of the organisms,\u201d Mason says.<\/p>\n<p>In that case, the alien microbe\u2019s genetic code could be sequenced on site, using a next-generation version of equipment that\u2019s already been tested on the International Space Station. Then the DNA data could be transmitted back to lab researchers on Earth.<\/p>\n<p>\u201cThey could synthesize it and then study it there with more resources, and send updates back to Mars,\u201d Mason says. \u201cYou could imagine this idea of a virtuous cycle of observation, interrogation, study, transfer of data, repeat in a place with more resources \u2014 and then send back that knowledge and help the organisms adapt.\u201d<\/p>\n<p>That\u2019s a world where Mickey wouldn\u2019t have to die every day.<\/p>\n<p>\u2014 \u25cf \u2014 <\/p>\n<p><em>\u201cThe Next 500 Years\u201d isn\u2019t Mason\u2019s only book. In collaboration with WorldQuant CEO Igor Tulchinsky, Mason has written a book delving into the rapid rise of artificial intelligence and big data, titled \u201cThe Age of Prediction: Algorithms, AI and the Shifting Shadows of Risk.\u201d Now he\u2019s working on a book about efforts to revive extinct and rare species, drawing upon his experience as an adviser to Colossal Laboratories &amp; Biosciences. Check out the Mason Lab\u2019s website to learn more about the researcher and his team at Weill Cornell Medicine.<\/em><\/p>\n<p><em>My co-host for the Fiction Science podcast is Dominica Phetteplace, an\u00a0award-winning writer\u00a0who is a graduate of the\u00a0Clarion West Writers Workshop\u00a0and lives in San Francisco. To learn more about Phetteplace, visit her website,\u00a0DominicaPhetteplace.com.<\/em><\/p>\n<p><em>Check out the original version of this report on Cosmic Log for bonus reading recommendations from Mason, and stay tuned for\u00a0future episodes of the\u00a0Fiction Science podcast\u00a0via\u00a0Apple,\u00a0Spotify,\u00a0Player.fm,\u00a0Pocket Casts\u00a0and\u00a0Podchaser.\u00a0Fiction Science is included in\u00a0FeedSpot\u2019s 100 Best Sci-Fi Podcasts. If you like Fiction Science, please rate the podcast and subscribe to get alerts for future episodes.<\/em><\/p>\n<\/p><\/div>\n<\/p><\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/www.universetoday.com\/articles\/how-humans-can-reinvent-themselves-to-live-on-other-worlds?rand=772204\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>By Alan Boyle March 8, 2025 Let\u2019s face it: Space is a hostile environment for humans. Even on Mars, settlers might have a hard time coping with potentially lethal levels&hellip; <\/p>\n","protected":false},"author":1,"featured_media":794182,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-794181","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genaero"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/794181","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=794181"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/794181\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/794182"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=794181"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=794181"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=794181"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}