Researchers discover new mechanism for Type IV pili retraction in Vibrio cholerae

Type IV pili, essential for many pathogens to cause disease, are hair-like appendages that grow out of and are retracted back into bacteria cells, enabling them to move and adhere to surfaces. Although pathogenic bacteria often rely on a specialized molecular motor to retract their pili, a new study in PLOS Pathogens reveals that a minor pilin protein elicits pilus retraction in the cholera bacterium, Vibrio cholerae.