First 3-D observation of nanomachines working inside cells

Currently, biologists who study the function of protein nanomachines isolate these complexes outside the cell in test tubes, and then apply in vitro techniques that allow them to observe their structure down to the atomic level. Alternatively, they use techniques that allow the analysis of these complexes within the living cell but that give little structural information. In this study, the scientists have directly observed the structure and function of the protein machinery in living cells.