Accurate DNA misspelling correction method

Researchers at the Institute of Basic Science (IBS) proved the accuracy of a recently developed gene editing method. This works as “DNA scissors” designed to identify and substitute just one nucleotide among the 3 billion. “It is the first time that the accuracy of this base editor has been verified at the whole genome level,” explains KIM Jin-Soo, leading author of the study. Published in Nature Biotechnology, this validation will help to expand the use of this method in agriculture, livestock, and gene therapy.