New protein regulated by cellular starvation

Researchers at the Center of Genomic Integrity, within the Institute for Basic Science (IBS), have found out an unexpected role for a protein involved in the DNA repair mechanism. The protein SHPRH not only helps to fix mistakes generated during DNA replication, but also contributes to the generation of new ribosomes, the cell’s “protein factories.” The newly discovered task depends on the nutritional state of the cell and might be associated with aging and anemia. This research has been recently published in the Proceedings of the National Academy of Sciences (PNAS).