Abstract: Hard X-ray observations are crucial to study the non-thermal jet emission from high-redshift, powerful blazars. We observed two bright z > 2 flat-spectrum radio quasars (FSRQs) in hard X-rays to explore the details of their relativistic jets and their possible variability. S50014+81 (at z = 3.366) and B0222+185 (at z = 2.690) have been observed twice by the Nuclear Spectroscopic Telescope Array (NuSTAR) simultaneously with Swift X-ray Telescope, showing different variability behaviors. We fou…