A research group from the University of Seville has revealed the role that the protein Rrm3 plays in the repair of breaks that occur during the replication of DNA, by using the yeast Saccharomyces cerevisiae as a model organism. This protein belongs to the human protein family PIF1, the mutations of which are known to be associated with a higher risk of tumorigenesis. This opens the possibility that the risk of suffering cancer might be due to the inability of the cell to repair correctly breaks in DNA that happen during replication.