Drosophilia brings to light the role of morphogens in limb growth

Researchers working in the Development and Growth Control Lab at IRB Barcelona reveal that the Dpp gene (BMP in humans) plays a double role in the structural organisation and growth of the wings of the fruit fly Drosophila melanogaster. This study, which has been published in the journal eLife, demonstrates that Dpp is necessary for tissue growth but that “its gradient does not direct wing growth,” explains Marco Milán, ICREA research professor and head of the study. This and two other studies published simultaneously in the journal eLife settle the intense scientific debate regarding the function of Dpp and other morphogens involved in development.