Noninvasive magnetic resonance imaging of lung fibrogenesis with an amino acid targeted probe

Organs respond to injuries with the formation of new fibrous tissue, which can result in scarring. This process called fibrogenesis can now be monitored noninvasively on a molecular level, as American scientists report in the journal Angewandte Chemie. They have created a new gadolinium-based probe for magnetic resonance imaging that specifically reports the proteins involved in fibrogenesis. The imaging method may provide a quantitative assessment of the formation of the potentially harmful scar tissue.