To commemorate the Wellcome Trust Sanger Institute turning 25 in 2018, the Institute and its collaborators are sequencing 25 new genomes. From the blackberry to the robin, bush cricket to brown trout, the 25 species all reside in the UK and represent the richness of species in this country. Twenty species have already been decided, and the remaining five will be voted for by the public and school children as part of ‘I’m a Scientist, Get Me Out of Here’.