The optogenetic method of controlling the position of proteins in cells using light is an important method to understand intracellular signal transduction. In conventional methods, short wavelength light, such as ultraviolet light or blue light, are commonplace. In 2009, Dr. Wendell A. Lim and others announced the PhyB-PIF system utilizing red light / near infrared light, but in order to use this system in animal cells, the cyanobacterial photosynthetic pigment phycocyanobilin (PCB) must be added. This step greatly hindered the use of the PhyB-PIF system.