Experiencing regret can leave a “bad taste” in one’s mouth and drive an individual to compensate for one’s losses. This immediate post-regret phenomenon was once thought to be unique to humans, but it has been recently demonstrated in other species. However, it was previously unknown if other species are capable of learning from these mistakes over time. New research from the University of Minnesota publishing 21 June in the open access journal PLOS Biology from authors Brian M. Sweis, Mark J. Thomas, and A. David Redish has now discovered that mice are capable of learning to plan ahead in order to avoid regret down the road even if there is no additional gain in rewards.