New method speeds up simulations, giving new insights into protein folding

A protein’s folding patterns help them perform their dedicated tasks. As the real “doers” of the cell, even a tiny alteration in a protein’s amino acid backbone can cause misfolding and hinder the protein’s functionality or cause disease. For instance, if tau, a protein that helps stabilize the structure of brain cells, is misfolded, it can form tau-tangles, which are commonly seen in Alzheimer’s patients.