Dietary nanoparticulates impact gut microbiome

The intestinal microbiome is not only key for food processing, but an accepted codeterminant for various diseases. Researchers led by the University Medical Center of Johannes Gutenberg University Mainz (JGU) identified effects of nanoparticles on intestinal microorganisms. The ultra-small particles adhere to intestinal microorganisms, thereby affecting their life cycle as well as cross talk with the host. One of the researchers’ observations was that nanoparticles’ binding inhibits the infection with Helicobacter pylori, a pathogen implicated in gastric cancer. The findings will stimulate further epidemiological studies and pave the way for the development of potential probiotic nanoparticles for food. The discoveries were published in Science of Food.