Tessellation is a repeating pattern made of one or more shapes, without the formation of gaps or overlaps. An example is the periodic arrangement of hexagonal cells found in honeycombs. Tessellation can also be found at the molecular level, where single molecule units act as a tile (repeating pattern) to tessellate a surface through spontaneous and reversible interactions between them. It is challenging to build complex molecular tessellation involving more than one type of tile. Most research studies in the past decade have focused on tessellation using a specific tile type.