Antibiotic-resistant bacteria are an increasing health threat, making new antibiotics essential. German researchers have recently had a breakthrough: they discovered lugdunin in the human nose—a new kind of cyclic peptide that comes from the bacterium Staphylococcus lugdunensis and has strong antimicrobial properties against Stahphylococcus aureus, among others. The researchers have been able to clarify the mode of action by synthesizing variants. As they explain in the journal Angewandte Chemie, proton transport across bacterial membranes is involved.
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Source: Phys.org