How the kava plant produces its pain-relieving and anti-anxiety molecules

Kava (Piper methysticum) is a plant native to the Polynesian islands that people there have used in a calming drink of the same name in religious and cultural rituals for thousands of years. The tradition of cultivating kava and drinking it during important gatherings is a cultural cornerstone shared throughout much of Polynesia, although the specific customs—and the strains of kava—vary from island to island. Over the past few decades, kava has been gaining interest outside of the islands for its pain-relief and anti-anxiety properties as a potentially attractive alternative to drugs like opioids and benzodiazepines because kavalactones, the molecules of medicinal interest in kava, use slightly different mechanisms to affect the central nervous system and appear to be non-addictive. Kava bars have been springing up around the United States, kava supplements and teas lining the shelves at stores like Walmart, and sports figures in need of safe pain relief are touting its benefits.


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Source: Phys.org