A group of Japanese researchers mainly from Tokyo University of Agriculture and Technology (TUAT) and Hokkaido University drastically enhanced and sped up the way to producing skeletally diverse indole alkaloids, composed of the medicinally-relevant scaffolds. By leveraging computational and synthetic approaches, this group has successfully developed a concise and versatile synthetic process generating densely-functionalized multicyclic complex scaffolds, which would facilitate the development of both medicine and agrochemicals.
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Source: Phys.org