Why initial UTIs increase susceptibility to further infection

Researchers have discovered that an initial UTI can set the tone for subsequent infections. In mouse studies, the researchers found that a transient infection triggers a short-lived inflammatory response that rapidly eliminates the bacteria. But a lingering infection leads to persistent inflammation and long-lasting changes to the bladder that prime the immune system to overreact to bacteria the next time, worsening the infection.


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Source: ScienceDaily