Analysis of global cancer data shines light on alternative gen 'switches' in tumors

Scientists from the Agency for Science, Technology and Research (A*STAR)’s Genome Institute of Singapore (GIS) have discovered that many human cancers exhibit widespread alterations in gene activation, where the same gene uses different start positions to generate alternate gene products. These alterations, previously undetected by earlier methods of analysis, may identify novel biomarkers for predicting cancer patient survival and new targets for therapies. The study was published in Cell on 5 September 2019 and featured on the journal’s cover.


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Source: Phys.org