Under JST’s Strategic Basic Research Programs, Noda Nobuo and Yamasaki Akinori at the Institute of Microbial Chemistry, in collaboration with other researchers, have discovered that autophagy is effective for selectively degrading protein in a liquid droplet state that is formed through liquid-liquid phase separation, but does poorly with the degradation of protein in aggregation or solid state.
Click here for original story, Autophagy degrades liquid droplets—but not aggregates—of proteins
Source: Phys.org