The family of ENDOU enzymes is found in most organisms, yet its functions are only poorly understood. In humans, it has been connected with cancer. RNA viruses, such as SARS-CoV2, contain a gene corresponding to ENDOU, and this is important for virus replication and the suppression of the immune response. However, so far only few details of the role of these enzymes are known. The research group led by the molecular geneticist Dr. Wenjing Qi from the University of Freiburg now contributes some more details to its function in a study published by the renowned scientific journal Nature Communications. They suggest that the gene ENDU-2 could be responsible for triggering tumors in the body from a distance. In addition, the team discovered a novel, seemingly contradictive response: Under stress, ENDU-2 can contribute both to the protection of the organism and to its destruction.
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Source: Phys.org