Despite long-standing interest, the cellular mechanisms driving the initiation of mammary gland development have remained elusive for decades, mostly due to technical limitations in studying dynamic cell behaviors in live tissues. Recent advances in microscopic methods and availability of various mouse models allowed the research group of Marja Mikkola from HiLIFE Institute of Biotechnology, University of Helsinki to address this question. This is the first time live tissue imaging has been used to visualize the emergence of the mammary gland.
Click here for original story, Cellular mechanisms of early mammary gland development unraveled
Source: Phys.org