Mapping the structure of the large molecular machine that activates mTOR

The principle that form follows function does not only apply to design and architecture. It also applies to biology. Every organism is a universe that lives thanks to the activities of tens of thousands of nanomachines, whose functions depend on their forms. Biologists say macromolecular complexes instead of nanomachines and structure instead of form, but the idea is the same: know the form and you will understand the function. Now, a group at the Spanish National Cancer Research Centre (CNIO) has helped determine the structure of a nanomachine essential for the functioning of another, mTOR, which plays fundamental roles in cancer and nutrition, aging and other vital processes in the body.


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Source: Phys.org