Total synthesis of the sesquiterpene agarozizanol B

Starting from available chemicals, a German team of researchers successfully completed the total synthesis of agarozizanol B, an interesting natural substance found in agarwood. As described in the journal Angewandte Chemie, the key sequence in the relatively short synthetic pathway is a photochemical reaction cascade that involves a series of complex rearrangements of polycyclic intermediates.


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Source: Phys.org