Researchers from Tokyo Metropolitan University have discovered how the sponginess and stickiness of stem cell nuclei controls how they “differentiate” into specialized cells. They found that the nucleus starts solid-like but becomes more fluid-like over time. Less force is transmitted to its inner parts, leaving cells to commit to a certain differentiation pathway. How stem cells choose and keep to differentiation paths continues to be a crucial question for medical science.
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Source: Phys.org