The existence of various molecular arrangements that occur in the solid-state is called polymorphism. During early-phase drug discovery, researchers commonly look at hydrogen-bonding networks to identify potential metastable polymorphs. But what if a system doesn’t have hydrogen bonding? Or what if the hydrogen-bonding networks are the same in two different solid forms?
Click here for original story, CSD-Materials suite provides a cohesive analysis of solid form properties for early-phase drug discovery
Source: Phys.org