In a new study published in Nature Chemical Biology, researchers at Children’s Hospital of Philadelphia (CHOP) have revealed the molecular mechanics of a cell-surface molecule that is a potential immunotherapy target. Using sophisticated techniques, including nuclear magnetic resonance (NMR) spectroscopy, the researchers demonstrated the importance of so-called chaperone molecules in stabilizing this target, known as MHC-I-related protein 1 (MR1).
Click here for original story, Researchers uncover molecular basis of antigen processing for cancer target MR1
Source: Phys.org