Differentiation of pluripotent stem cells (PSCs) is regulated through a methionine-mediated mechanism, which has now been pinpointed by Tokyo Tech researchers. They have revealed that zinc (Zn) plays a crucial role in PSC potentiation. They used these insights to design a protocol to convert PSCs into insulin-producing pancreatic β cells—a high-potential diabetes therapy.
Click here for original story, The zinc link: Unraveling the mechanism of methionine-mediated pluripotency regulation
Source: Phys.org