New method enables efficient sample preparation for single-cell proteomics

The proteins that make up our cells hold within an entire world of information, which, when unlocked, can give us insights into the origins of many essential biological phenomena. This information is gathered using an analytical technique known as “single-cell proteomics,” in which a single-cell analysis is performed to observe the characteristics of individual cells at their protein level. Over the years, scientists have used single-cell proteomics in the fields of cancer genomics, cell differentiation, and tissue development. However, current proteomics techniques suffer from low recovery rate of protein samples, low throughput, and lack of versatility.


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Source: Phys.org