For four decades, Specificity Protein 1 (Sp1) has been cast solely as a transcription factor, a type of protein that binds DNA and turns genes on. But a Donnelly Center study has now revealed that Sp1 plays another unexpected role in gene regulation by influencing the stability of genes’ RNA messages.
Click here for original story, The double life of Sp1: A protein’s new role upends thinking about its impact on cancer
Source: Phys.org