Animal studies on great apes have long been banned in Europe for ethical reasons. For the question pursued here, organoids (three-dimensional cell structures a few millimeters in size that are grown in the laboratory) are an alternative to animal experiments. These organoids can be produced from pluripotent stem cells, which then differentiate into specific cell types, such as nerve cells. In this way, the research team was able to produce both chimpanzee brain organoids and human brain organoids. “These brain organoids allowed us to investigate a central question concerning ARHGAP11B,” says Wieland Huttner of the MPI-CBG, one of the three lead authors of the study published in EMBO Reports.
Click here for original story, Brain organoids provide insights into the evolution of the human brain
Source: Phys.org