PDGFR kinase inhibitor found to protect against septic death via regulation of BTLA

In a study was led by Dr. Jianxin Jiang (Institute of Department of Trauma Medical Center, Daping Hospital, State Key Laboratory of Trauma, Burns and Combined Injury, Army Medical University), a team screened a highly selective kinase inhibitor library and found that CP-673451 can upregulate BTLA expression on immunocytes and reduce sepsis-related mortality.


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Source: Phys.org