Autophagy is a self-degradation process that cells use to remove unneeded or damaged components. There are several forms of autophagy, including macroautophagy, which is a bulk degradation system used to target materials in the cell’s cytosol to organelles called lysosomes for enzymatic breakdown. However, even lysosomes themselves sometimes need to be degraded. Recently, Osaka University researchers examined the specific molecular details of how damaged lysosomes are selected and marked for clearance.
Click here for original story, Molecular tags reveal how damaged lysosomes are selected and marked for clearance
Source: Phys.org