Researchers have discovered the mechanistic steps underlying a new type of synaptic plasticity called behavioral timescale synaptic plasticity (BTSP). The study reveals how the entorhinal cortex (EC) sends instructive signals to the hippocampus — the brain region critical for spatial navigation, memory encoding, and consolidation — and directs it to specifically re-organize the location and activity of a specific subset of its neurons to achieve altered behavior in response to its changing environment and spatial cues.
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Source: ScienceDaily