The widely used gene scissor (CRISPR/Cas) can modify the genetic content in cells to study the molecular roles of genes and has gained great clinical relevance in gene therapy to treat genetic diseases. A new study performed by Claudia Kutter’s research group at the Department of Microbiology, Cell, and Tumor Biology at Karolinska Institutet, found that the gene scissor leads to unexpected genomic changes.
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Source: Phys.org