Overcoming challenges in the delivery of nucleic acid therapeutics

Nucleic acid therapies involving DNA or RNA have significant potential to treat genetic disorders, infectious diseases, and cancer; however, research suggests that less than 1% of injected nucleic acid doses reach target cells in an active form. An article in WIREs Nanomedicine and Nanobiotechnology highlights two of the major barriers to this therapeutic strategy, and how they might be overcome.


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Source: Phys.org