Hybridization chain reaction refers to an enzyme-free nucleic acid polymerization reaction. A target molecule triggers cascade hybridization reactions by several thermodynamically stable DNA fuel strands, producing ultra-long DNA nanostructures with nicks. Signal amplification of the target molecule can be achieved by the application of a hybridization chain reaction.
Click here for original story, Scientists develop novel mode of linear hybridization chain reaction
Source: Phys.org