Transcription factors are proteins that interact with DNA to regulate the function of some genes. Generally, a single transcription factor binds to several regions in the genome as it orchestrates complex cellular responses, which require the activation or inhibition of several genes. FoxH1 is an essential transcription factor during embryonic development, and, in adults, it is related to the progression of lung cancer and some types of leukemia.
Click here for original story, 3D models reveal, at the atomic scale, how FoxH1 binds to specific points in the genome
Source: Phys.org