Ribosomes search AUG codons in bidirectional scanning, challenging the first-AUG rule

Translation, a process that expresses the genetic information from messenger RNA (mRNA) to protein, is vital to maintain cellular protein homeostasis. To synthesize functional proteins and avoid toxic translation products, the recognition of the correct initiation codon (AUG) by the small ribosomal subunit is crucial.


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Source: Phys.org